Document Details Document Type : Article In Journal  Document Title : Recombinant tissue plasminogen activator for acute ischemic stroke Recombinant tissue plasminogen activator for acute ischemic stroke   Document Language : English  Abstract : Stroke is a leading cause of serious and long-term disability and death worlwide, with approximately 750,000 strokes occuring annually in the United States of America. The risk of stroke doubles each decade for people over 55 years. Cerebral angiography conducted soon after the onset of stroke demonstrates arterial occlusion in 70%-80% of cases. Recanalization of an occluded cerebral artery may assist in the recovery of reversibly ischemic tissue and limit the neurological disability. In June 1996, the recombinant tissue plasminogen activator was approved as a safe and an effective intravenous treatment for acute ischemic stroke, especially if given within 3 hours of onset of symptoms. Since approval, less than 5% of all stroke patients are receiving recombinant tissue plasminogen activator. In this review we try to answer the question of whether recombinant tissue plasminogen activator therapy should be the first-line treatment for acute ischemic stroke. The result of major recombinant tissue plasminogen activator trials will be summarized and reviewed critically  ISSN : 1658-3183  Journal Name : Neurosciences  Volume : 7  Issue Number : 1  Publishing Year : 1423 AH 2002 AD  Article Type : Article  Added Date : Saturday, May 10, 2008  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email محمد جان Jan, Mohammed Researcher Doctorate   Files File Name Type Description  rt-PA_for_Stroke.pdf pdf مشاهدة المقالة العلمية كاملة Back To Researches Page