Document Details

Document Type : Article In Journal 
Document Title :
Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
 
Document Language : English 
Abstract : AIM: To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. METHODS: 19 patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. RESULTS: 8/19 patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. CONCLUSION: Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated. 
ISSN : 1468-2079 
Journal Name : British Journal of Ophthalmology 
Volume : 85 
Issue Number : 10 
Publishing Year : 1422 AH
2001 AD 
Article Type : Article 
Added Date : Monday, August 31, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سعد وهيبWaheeb, Saad ResearcherDoctorate 

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