Document Details

Document Type : Article In Journal 
Document Title :
Systemic Lupus Erythematosus in Saudi Arabia: morbidity and mortality in a multiethnic population
Systemic Lupus Erythematosus in Saudi Arabia: morbidity and mortality in a multiethnic population
 
Document Language : English 
Abstract : The objective of this study is to summarize the features of patients with Lupus erythematosus in Saudi Arabia. Racial differences of patients and predictors of mortality are assessed. Ninety-three patients treated for SLE at the University Hospital in Jeddah were reviewed. Frequencies of clinical manifestations, causes of admission and causes of death were analysed. Variables predicting mortality were assessed by logistic regression and survival probabilities were estimated by the Kaplan-Meier method. The most frequent presenting symptoms were arthritis (68%) and fever (58%). Renal involvement was seen in 61% of patients. The majority of patients (61%) showed ANA titers higher than 1:1280. C4 levels were significantly lower in patients who died during the observation period than in survivors. The overall five-year survival rate was 92%. Variables predicting early death (<2 years after diagnosis) were young age at diagnosis, male sex and skin involvement. Death after more than two years correlated with older age at diagnosis and renal involvement. Patients of African descent had higher rates of neurological involvement and renal failure. The mortality in this group was highest, though this was not statistically significant. The overall survival in our cohort compares with mortality rates reported from western countries. However, renal disease tends to be common and has a severe prognosis, and thus merits additional attention 
ISSN : 0961-2033 
Journal Name : Lupus 
Volume : 16 
Issue Number : 11 
Publishing Year : 1428 AH
2007 AD
 
Article Type : Article 
Added Date : Monday, October 12, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ميمونة أحمدAhmed, Maimoona ResearcherDoctorate 
عائشة صديقيSiddiqui, Aisha ResearcherDoctorate 
سامي بحلسBahlas, Sami ResearcherDoctorate 

Files

File NameTypeDescription
 28932.pdf pdf 

Back To Researches Page