Document Details
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Document Type |
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Article In Journal |
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Document Title |
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SUSCEPTIBILITY TO ANTIBIOTICS OF BACTERIA ISOLATED FROM LOWER RESPRRATORY TRACT INFECTIONS DURING 1991 & 1992 PILGRIMAGE (HAJ) SEASONS SUSCEPTIBILITY TO ANTIBIOTICS OF BACTERIA ISOLATED FROM LOWER RESPRRATORY TRACT INFECTIONS DURING 1991 & 1992 PILGRIMAGE (HAJ) SEASONS |
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Document Language |
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English |
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Abstract |
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One hundred and eighteen bacterial specimens were isolated as possible causative pathogens from sputum of patients with lower respiratory tract infections during 1991 and 1992 pilgrimage seasons. Of these isolates, 42 were H. influenzae, 31 K. pneumoniae, 27 Strept. pneumoniae, 11 Staph. aureus and 7 Strept. pyogenes. Isolates were tested for susceptibility patterns to various antimicrobial agents which were chosen based on prevailing usage in respiratory tract infection. Cefotaxime and cefuroxime were the most active antibacterials against all the isolated strains, followed by chloramphenicol, tetracycline and ampicillin.
Among 1991 H. Influenzae isolates resistance to cefotaxime, cefuroxime, ampicillin and tetracycline were 3.4%, 10.3%, 10.3 and 20.7%, respectively. Resistance to sulfonamide was moderately high in both 1991 and 1992 isolates, being 20.7% and 23%, respectively.
All the K. pneumoniae isolates were sensitive to amoxycillin clavulanate, cefotaxime, cefuroxime, gentamicin, amikacin, tobramycin, aztreonam and trimethoprim/sulfamethoxazole. Susceptibility to tetracycline and chloramphenicol increased from 20% in 1991 to 100% in 1992. However, susceptibility to ampicillin fell from 20% in 1991 to zero in 1992. No change was observed in the susceptibility pattern of St. pneumoniae and St. pyogenes in the two study periods and all isolates were susceptible to amoxycillin/clavulanate, ampicillin, amoxycillin, penicillin, chloramphenicol, tetracycline, cefotaxime, cefuroxime, vancomycin and erythromycin.
The overall rates of resistance of Staph. aureus to the different antibiotics tested were: penicillin 45.5%, erythromycin 36%, ampicillin 45.5%, tetracycline 45.5% cefotaxime 18%, rifampicin 18% and cefuroxime 9%. All isolates were sensitive to amoxycillin/clavulanate, chloramphenicol, gentamicin, tobramycin, fusidin, methicillin and vancomycin |
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ISSN |
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16885634 |
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Journal Name |
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Arab.J..Lab.med |
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Volume |
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22 |
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Issue Number |
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2 |
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Publishing Year |
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1416 AH
1996 AD |
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Article Type |
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Article |
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Added Date |
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Sunday, May 30, 2010 |
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Researchers
| سليمان الشيخ | EL-sheikh, Soliman | Researcher | Doctorate | |
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