Document Details

Document Type : Article In Journal 
Document Title :
SOME PHARMACOLOGICAL AND ANTIBACTERIAL PROPERTIES OF NIGELLA SA TI VA SEEDS EXTRACTS IN EXPERIMENTAL ANIMALS
SOME PHARMACOLOGICAL AND ANTIBACTERIAL PROPERTIES OF NIGELLA SA TI VA SEEDS EXTRACTS IN EXPERIMENTAL ANIMALS
 
Document Language : English 
Abstract : Nigella sativa powdered seeds und/or some of its aqueous or alcoholic extracts were found to have hypoglycemic effect when administered to both normal and alloxan-treated diabetic rats. This hypoglycemic effect could be due to enhanced release of insulin from the pancreas or by inhibiting gluconeogenesis or by increasing glucose uptake in peripheral tissues. The extracts also lowered the arterial blood pressure in both rabbits and guinea pigs by both central and peripheral mechanisms. In addition both the extracts and volatile oil of the seeds had anti-inflammatory activity in carrageenin induced oedema in the rat’s paw. Neither the crude oil of the seeds nor the alcoholic extracts had any significant effect on some liver enzymes when they were given daily for one months to rats. Finally organic extracts of the seeds showed antibacterial activity against some Gram-positive and gram-negative bacilli. 
ISSN : 19327302 
Journal Name : J.Egypt. Soc. Pharmacol Exp.ther. 
Volume : 19 
Issue Number : 2 
Publishing Year : 1420 AH
2000 AD 
Article Type : Article 
Added Date : Sunday, May 30, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سليمان الشيخEL-sheikh, Soliman ResearcherDoctorate 

Files

File NameTypeDescription
 26878.doc doc 

Back To Researches Page