Document Details Document Type : Article In Journal  Document Title : Chemoembolization in Metastatic Liver Neoplasms KAD R Experience Chemoembolization in Metastatic Liver Neoplasms KAD R Experience   Document Language : English  Abstract : ABSTRACT. Objective: To assess the results of chemoembolizationin this pi¬lot study for patients with unresectable metastatic liver neoplasms. Methods: Patients with unresectable liver metastases secondary to different primary tumors who did not have decompesated liver disease underwent se¬lective intra-arterial chemotherapy consisting of 5-flourouracil,adriamycin and cisplatin followed by embolization of the feeding artery using Poly Vinyl Al-cohol Particles (PV AP). Courses of treatment were given every four to six weeks for a minimum of three courses. Results: Eight patients with bilateral multiple or diffuse liver metastasis un¬derwent chemoembolization. Five out of eight patients had good palliation of symptoms and improvement in their quality of life. Their average duration of palliation was 7.2 months. Median survival for all patients was seven months. Seven patients died within the first year from a diagnosis of liver metastasis. The last patient with carcinoid syndrome is still alive 36 months after di¬agnosis. Conclusion: Selective intra-arterial chemotherapy followed by embolization in this pilot study with unresectable liver metastases gives palliation of symp¬toms and improvement in the quality of life for almost half of our patients but for a short duration. Patients with neuroendocrine tumors may have longer du¬ration of palliation and survival. Further randomized trials with a higher num¬ber of patients would be worthwhilepursuing. Keywords: Liver, Neoplasm. Arteries, Chemoembolization.  ISSN : 1110-5607  Journal Name : Saudi Medica  Volume : 7  Issue Number : 1  Publishing Year : 1420 AH 1999 AD  Article Type : Article  Added Date : Friday, January 14, 2011  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email محمود الاحول AI-Ahwal, Mahmoud Researcher Doctorate   Files File Name Type Description  28613.doc doc   Back To Researches Page